Aging

Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses
Host defense against bacterial and fungal infections diminishes with age. In humans, impaired neutrophil responses are thought to …
Kirsti Hornigold, Julia Y. Chu, Stephen A. Chetwynd, Polly A. Machin, Laraine Crossland, Chiara Pantarelli, Karen E. Anderson, Phillip T. Hawkins, Anne Segonds-Pichon, David Oxley, Heidi C. E. Welch
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P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination
The small GTPase Rac controls cell morphology, gene expression, and reactive oxygen species formation. Manipulations of Rac activity …
Sarah Donald, Trevor Humby, Ian Fyfe, Anne Segonds-Pichon, Simon A. Walker, Simon R. Andrews, W. John Coadwell, Piers Emson, Lawrence S. Wilkinson, Heidi C. E. Welch
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