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Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1
P-Rex1 is a guanine-nucleotide exchange factor (GEF) that activates the small G protein (GTPase) Rac1 to control Rac1-dependent …
Dingxin Pan
,
Mark A. Barber
,
Kirsti Hornigold
,
Martin J. Baker
,
Judit M. Toth
,
David Oxley
,
Heidi CE Welch
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DOI
P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination
The small GTPase Rac controls cell morphology, gene expression, and reactive oxygen species formation. Manipulations of Rac activity …
Sarah Donald
,
Trevor Humby
,
Ian Fyfe
,
Anne Segonds-Pichon
,
Simon A. Walker
,
Simon R. Andrews
,
W. John Coadwell
,
Piers Emson
,
Lawrence S. Wilkinson
,
Heidi C. E. Welch
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DOI
A neutral phospholipase D activity from rat brain synaptic plasma membranes. Identification and partial characterization
Rapid activation of phospholipase D (PLD) in response to cell stimulation was recently demonstrated in many systems, raising the …
V. Chalifa
,
H. Möhn
,
M. Liscovitch
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