Guanine Nucleotide Exchange Factor

P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells
P-Rex1 is a guanine-nucleotide exchange factor (GEF) that activates Rac-type small G proteins in response to the stimulation of a range …
Elizabeth Hampson, Elpida Tsonou, Martin J. Baker, David C. Hornigold, Roderick E. Hubbard, Andrew Massey, Heidi C. E. Welch
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Rho Family GTPases and Rho GEFs in Glucose Homeostasis
Dysregulation of glucose homeostasis leading to metabolic syndrome and type 2 diabetes is the cause of an increasing world health …
Polly A. Machin, Elpida Tsonou, David C. Hornigold, Heidi C. E. Welch
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