Lipopolysaccharides

Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses
Host defense against bacterial and fungal infections diminishes with age. In humans, impaired neutrophil responses are thought to …
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation
The small GTPase Rac is required for neutrophil recruitment during inflammation, but its guanine-nucleotide exchange factor (GEF) …