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PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis
The Rac-GEF, P-Rex1, activates Rac1 signaling downstream of G protein-coupled receptors and PI3K. Increased P-Rex1 expression promotes …
Nuthasuda Srijakotre, Heng-Jia Liu, Max Nobis, Joey Man, Hon Yan Kelvin Yip, Antonella Papa, Helen E. Abud, Kurt I. Anderson, Heidi C. E. Welch, Tony Tiganis, Paul Timpson, Catriona A. McLean, Lisa M. Ooms, Christina A. Mitchell
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A Rac1-Independent Role for P-Rex1 in Melanoblasts
Colin R. Lindsay, Ang Li, William Faller, Brad Ozanne, Heidi Welch, Laura M. Machesky, Owen J. Sansom
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Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase
Long-term potentiation (LTP) at the parallel fibre-Purkinje cell synapse in the cerebellum is a recently described and poorly …
Claire Jackson, Heidi C. Welch, Tomas C. Bellamy
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A neutral phospholipase D activity from rat brain synaptic plasma membranes. Identification and partial characterization
Rapid activation of phospholipase D (PLD) in response to cell stimulation was recently demonstrated in many systems, raising the …
V. Chalifa, H. Möhn, M. Liscovitch
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