PREX1

The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses
textlessptextgreaterRac GTPases are required for neutrophil adhesion and migration, and for the neutrophil effector responses that kill …
Kirsti Hornigold, Martin J. Baker, Polly A. Machin, Stephen A. Chetwynd, Anna-Karin Johnsson, Chiara Pantarelli, Priota Islam, Melanie Stammers, Laraine Crossland, David Oxley, Hanneke Okkenhaug, Simon Walker, Rachael Walker, Anne Segonds-Pichon, Yoshinori Fukui, Angeliki Malliri, Heidi C. E. Welch
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Small-molecule inhibitors of P-Rex guanine-nucleotide exchange factors
P-Rex1 and P-Rex2 are guanine-nucleotide exchange factors (GEFs) that activate Rac small GTPases in response to the stimulation of G …
C. D. Lawson, K. Hornigold, D. Pan, I. Niewczas, S. Andrews, J. Clark, Hce Welch
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