Protein Binding

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1
P-Rex1 is a guanine-nucleotide exchange factor (GEF) that activates the small G protein (GTPase) Rac1 to control Rac1-dependent …
Dingxin Pan, Mark A. Barber, Kirsti Hornigold, Martin J. Baker, Judit M. Toth, David Oxley, Heidi CE Welch
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Regulation and function of P-Rex family Rac-GEFs
The P-Rex family are Dbl-type guanine-nucleotide exchange factors for Rac family small G proteins. They are distinguished from other …
Heidi CE Welch
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Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits
P-Rex1 is a guanine-nucleotide exchange factor (GEF) for the small GTPase Rac. We have investigated here the mechanisms of stimulation …
Kirsti Hill, Sonja Krugmann, Simon R. Andrews, W. John Coadwell, Peter Finan, Heidi C. E. Welch, Phillip T. Hawkins, Len R. Stephens
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