Tumor Microenvironment

The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment
Numerous large scale genomics studies have demonstrated that cancer is a molecularly heterogeneous disease, characterized by acquired …
Marina Pajic, David Herrmann, Claire Vennin, James Rw Conway, Venessa T. Chin, Anna-Karin E. Johnsson, Heidi CE Welch, Paul Timpson
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P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments
Expression of the Rac-guanine nucleotide exchange factor (RacGEF), P-Rex1 is a key determinant of progression to metastasis in a number …
Andrew D. Campbell, Samuel Lawn, Lynn C. McGarry, Heidi C. Welch, Bradford W. Ozanne, Jim C. Norman
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